Differential amplifiers are used mainly to suppress noise.
Noise consists of typical differential noise and common-mode noise, of which the latter can easily be suppressed with an op-amp.
There are two main causes of common-mode noise:
-Noise is generated in the wires and cables, due to electromagnetic induction, etc., and it causes a difference in potential (i.e., noise) between the signal source ground and the circuit ground.
-Current flowing into the ground of a circuit from another circuit causes a ground potential rise (noise).
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